Pineapple Bromelain: The Natural Powerhouse for Skin Whitening, Antioxidation, and Anti-Aging

Bromelain, an enzyme derived from pineapple, has emerged as a potent natural ingredient with remarkable skin benefits, including whitening, antioxidation, and anti-aging properties. Its unique composition, rich in proteins and active compounds, supports its widespread application in cosmetic and skincare formulations.

The enzyme exhibits strong biological activities such as antioxidant effects (DPPH inhibition IC50 = 2.02 mg/mL) and anti-tyrosinase activity (L-Dopa inhibition IC50 = 0.15 mg/mL), making it effective in reducing oxidative stress and inhibiting melanin production for skin brightening. Bromelain also demonstrates anti-aging properties by inhibiting enzymes like collagenase, elastase, and hyaluronidase, which are responsible for skin degradation and aging.

Toxicity assessments confirm that bromelain is safe for human use, being non-cytotoxic to skin and other cell lines. Additionally, its solubility in various solvents and compatibility with cosmetic formulations enhance its applicability in skincare products.

This research underscores the potential of bromelain as a sustainable and effective ingredient in natural skincare solutions, aligning with the global demand for eco-friendly and functional cosmetic products.